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The amount of time that wild-type (upper panel) and knockout (lower panel) mice spent in CPP chambers before (D1) and after (D10) repeated conditioning with M6G (10 mg/kg) and following a saline (D14) or M6G (5 mg/kg, D15) challenge. The data represent the mean (±S.E.M.) of 6 mice per genotype. *significantly different compared to their respective chamber on day 1 (p<0.05)
