Expression levels of GABAA receptor α1 and α2 subunit mRNAs in the monkey DLPFC during development. The optical densities for α1 (A) and α2 (B) subunit mRNAs within area 46 are individually plotted for each age group. The mean values for each age group are indicated as bars. During postnatal development, α1 mRNA levels increased, whereas α2 mRNA levels declined. Age groups that do not share the same letter are statistically different at α ≤ 05. Note that the shift in α subunit expression is a progressive and protracted process that lasts through adolescence. M, months; Pre, prepuberty; Post, postpuberty; W, week.
From Hashimoto et al. (2009).