Figure 1. Blood biomarkers in patients with neuromyelitis optica.
Concentration of IL-17A (A), IL-17F (B) CXCL5 (C), CXCL8 (D), IL-5 (E), Eotaxin I (F), IL-12p40 (G) and IL-12p70 (H) IFN-β (I), IP10 (J) in serum of six patients with Neuromyelitis optica (NMO) with spinal cord lesions greater than three vertebral segments (MR>3seg) and 10 patients with NMO with spinal cord lesions less than three vertebral segments (MR<3seg). Cytokine concentrations were measured by Luminex multiplex assay and calculated from a standard linear regression of known quantities of each cytokine. Neutrophil elastase (K) was measured in plasma from six NMO patients and seven healthy volunteers by ELISA. Data are represented as mean ± SEM and p-values from two-tailed Student’s t-tests are shown.