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. Author manuscript; available in PMC: 2012 Apr 5.
Published in final edited form as: Mult Scler. 2012 Feb 16;18(4):398–408. doi: 10.1177/1352458512440060

Figure 3. Type I IFN synergizes with complement to release neutrophil elastase from neutrophils.

Figure 3

(A) Representative immunofluorescence stainings of neutrophil elastase (red), histone (green) and DNA (blue) in human neutrophil cultures stimulated with media only, C5a, IFN-β and C5a + IFN-β for 4h. 20×. (B) Quantification of mean number of neutrophil extracellular traps (NETs) in neutrophil cultures of four healthy controls stimulated with media only, C5a, IFN-β and C5a + IFN-β. p-value from a two-tailed Student’s t-test is shown.