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Cladogram of human Src family kinases (SFKs) and sequence alignment of their SH3 domains. A. A phylogenetic tree of human SFKs, which is based on the similarity of their catalytic domains, and adapted from another publication [41]. B. The sequences of SH3 domains of SFKs were aligned to reveal their amino acid identity to the Fyn SH3 domain; conserved residues are highlighted in gray columns, and dashes are introduced to maximize alignment.
