Table 5.
Predictive value of microbial profile for ‘ongoing infection needing relaparotomy’ in patients with culture available from index laparotomy (n = 158)
| Analysis | Ongoing infection needing relaparotomy (N = 49) | No ongoing infection, not needing relaparotomy (N = 109) | OR | 95% CI | P | ||
|---|---|---|---|---|---|---|---|
| Univariate analysis | |||||||
| Monomicrobiala | 11 | (23%) | 19 | (20%) | 0.84 | 0.36–1.5 | 0.686 |
| Microbial profile | |||||||
| Negative culture result | 2 | (4%) | 16 | (15%) | 0.25 | 0.06–1.12 | 0.070 |
| Coliform | 12 | (25%) | 29 | (27%) | 0.90 | 0.41–1.95 | 0.779 |
| Gram (+) cocci | 6 | (12%) | 12 | (11%) | 1.13 | 0.40–3.20 | 0.821 |
| Coliforms and gram (+) cocci | 26 | (53%) | 47 | (43%) | 1.49 | 0.76–2.94 | 0.247 |
| Only anaerobes | 2 | (4%) | 3 | (3%) | 1.50 | 0.24–9.30 | 0.661 |
| Yeast present | 10 | (20%) | 25 | (23%) | 0.86 | 0.38–1.97 | 0.724 |
| Pseudomonas present | 2 | (4%) | 11 | (11%) | 0.38 | 0.08–1.78 | 0.219 |
| Amoxicilline resistant gram (+) coccib | 6 | (15%) | 5 | (5%) | 3.27 | 0.94–11.45 | 0.063 |
| Gentamicin resistant coliformsb | 3 | (8%) | 1 | (1%) | 7.83 | 0.79–77.78 | 0.079 |
| Multi drug resistanceb | 31 | (79%) | 63 | (66%) | 1.36 | 0.60–3.06 | 0.465 |
| Multivariate analysisb | |||||||
| Negative culture result | 2 | (5%) | 16 | (17%) | 0.29 | 0.06–1.35 | 0.189 |
| Amoxicilline resistant gram (+) cocci | 6 | (15%) | 5 | (5%) | 3.43 | 0.95–12.38 | 0.060 |
| Gentamicin resistant coliforms | 3 | (8%) | 1 | (1%) | 7.61 | 0.75–76.94 | 0.085 |
| Perforation or ischemia | 23 | (59%) | 65 | (68%) | 0.67 | 0.30–1.52 | 0.342 |
OR odds ratio, CI confidence interval
a Regression analysis in 140 patients with positive culture result (47 ongoing infection, 93 no ongoing infection), since patients without growth are in neither of the categories.
b Regression analysis in 134 patients with known susceptibility or negative culture result (39 ongoing infection, 95 no ongoing infection).