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. 2012 Apr 5;2:354. doi: 10.1038/srep00354

Figure 1. Conservation profile and Pfam domain prediction of CARN7_2759.

Figure 1

The graph displays the conservation profile deduced from the multiple alignment of 200 protein sequences obtained from PipeAlign using CARN7_2759 as a query. For each residue of CARN7_2759 protein sequence, this profile shows the number of identical amino-acids at the corresponding position of the multiple sequence alignment. The black boxes show the TraC signature (Pfam:PF11130 from 33 to 275) and the AAA domain (Pfam:PF12846 from 474 to 758) predicted by InterProScan. Both Walker A and Walker B motifs (grey boxes) characteristic of AAA domains could be identified in this region (respectively from 481 to 489, and from 686 to 693) and correspond to peaks of conservation.