Table 4.
Toxicity, dosage modifications and chemotherapy discontinuation n (%)
| Patients | |
| Clinical toxicity grade 3-4 | |
| Nausea | 3 (3.7) |
| Vomiting | 5 (6.2) |
| Diarrhea | 2 (2.4) |
| Stomatitis | 1 (1.2) |
| Fever | 6 (7.5) |
| Infection | 6 (7.5) |
| Haematological toxicity grade 3-4 | |
| Anemia | 2 (2.4) |
| Neutropenia | 14 (17.1) |
| Thrombocytopenia | 1 (1.2) |
| Dosage modifications | 41 (51.3) |
| Type | |
| Treatment suppression | 7 (17.1) |
| Dose reduction | 17 (41.5) |
| Delay of cycle | 33 (80.5) |
| Discontinuation before evaluation | 31 (41.3) |
| Progressive disease | 23 (74.2) |
| Toxicity | 3 (9.7) |
| Chemotherapy-related deaths | 5 (16.1) |