Table 1.
Week (W) of Treatment | Female | Male | ||||||
---|---|---|---|---|---|---|---|---|
Vehicle | EEZZ (mg kg−1 per day) | Vehicle | EEZZ (mg kg−1 per day) | |||||
1000 | 2000 | 3000 | 1000 | 2000 | 3000 | |||
Body weight (g) | ||||||||
W1 | 212.97 ± 15.97 | 214.83 ± 13.42 | 215.32 ± 16.41 | 218.92 ± 13.56 | 223.61 ± 16.48 | 225.58 ± 14.59 | 229.26 ± 16.41 | 228.12 ± 15.92 |
W2 | 229.60 ± 14.75 | 224.67 ± 14.87 | 219.83 ± 19.26 | 223.97 ± 16.92 | 241.08 ± 15.24 | 235.90 ± 16.11 | 241.81 ± 13.88 | 246.37 ± 19.61 |
W3 | 245.11 ± 17.36 | 249.32 ± 15.96 | 233.51 ± 13.88 | 241.28 ± 15.86 | 257.36 ± 17.91 | 261.78 ± 17.26 | 256.68 ± 19.26 | 265.41 ± 20.15 |
W4 | 244.72 ± 12.63 | 245.21 ± 17.81 | 237.72 ± 14.72 | 243.81 ± 17.41 | 256.96 ± 13.08 | 257.47 ± 18.90 | 261.49 ± 14.72 | 268.19 ± 18.44 |
| ||||||||
Food intake (g day−1 per rat) | ||||||||
W1 | 22.86 ± 4.04 | 25.95 ± 3.01 | 25.29 ± 2.84 | 24.66 ± 3.12 | 24.13 ± 4.13 | 26.23 ± 3.47 | 26.36 ± 4.15 | 26.17 ± 4.21 |
W2 | 20.31 ± 3.69 | 22.25 ± 2.94 | 21.62 ± 3.14 | 20.44 ± 3.68 | 23.16 ± 4.45 | 23.32 ± 4.17 | 23.52 ± 3.69 | 23.52 ± 3.68 |
W3 | 22.40 ± 3.87 | 20.83 ± 3.74 | 21.11 ± 3.49 | 21.45 ± 4.95 | 23.21 ± 4.17 | 22.39 ± 3.49 | 22.32 ± 4.18 | 23.58 ± 3.95 |
W4 | 19.70 ± 3.94 | 20.59 ± 4.78 | 21.70 ± 4.32 | 20.97 ± 3.34 | 20.08 ± 3.62 | 21.74 ± 3.35 | 22.58 ± 3.93 | 23.14 ± 4.87 |
| ||||||||
Water intake (ml day−1 per rat) | ||||||||
W1 | 24.12 ± 5.62 | 25.63 ± 6.25 | 24.08 ± 6.61 | 24.37 ± 5.12 | 25.32 ± 6.18 | 26.38 ± 6.38 | 25.28 ± 7.41 | 25.37 ± 6.12 |
W2 | 25.09 ± 8.61 | 25.82 ± 5.61 | 24.62 ± 7.92 | 24.19 ± 6.83 | 26.34 ± 9.47 | 26.11 ± 6.15 | 25.85 ± 6.76 | 25.91 ± 7.38 |
W3 | 26.17 ± 5.09 | 25.56 ± 6.52 | 26.51 ± 8.12 | 23.82 ± 7.14 | 27.47 ± 5.59 | 26.83 ± 5.28 | 27.83 ± 7.31 | 26.27 ± 8.01 |
W4 | 24.41 ± 4.97 | 24.09 ± 5.18 | 25.41 ± 6.34 | 25.43 ± 7.27 | 25.63 ± 5.47 | 25.29 ± 5.18 | 25.41 ± 8.12 | 25.96 ± 6.98 |
Wistar rats (n = 10 per group) were administered ZZEE by daily gavage for 4 weeks. Data are expressed as mean ± SD.