Table 2.
Effects of subchronic oral administration of the ethanol extract of Z. zerumbet rhizomes (EEZZ) on haematological parameters of Wistar rats.
| Parameters | Female | Male | ||||||
|---|---|---|---|---|---|---|---|---|
| Vehicle | EEZZ (mg kg−1 per day) | Vehicle | EEZZ (mg kg−1 per day) | |||||
| 1000 | 2000 | 3000 | 1000 | 2000 | 3000 | |||
| WBC (103 μL−1) | 9.09 ± 0.59 | 8.69 ± 0.62 | 8.78 ± 0.57 | 8.61 ± 0.64 | 9.20 ± 0.68 | 8.90 ± 0.70 | 8.59 ± 0.73 | 8.76 ± 0.64 |
| Lymphocytes (103 μL−1) | 6.76 ± 0.40 | 6.66 ± 0.65 | 6.58 ± 0.35 | 7.14 ± 0.65 | 6.92 ± 0.75 | 7.36 ± 0.63 | 7.52 ± 0.60 | 7.86 ± 0.71 |
| Erythrocytes (106 μL−1) | 7.29 ± 0.07 | 7.69 ± 0.10 | 7.70 ± 0.08 | 7.76 ± 0.11 | 7.43 ± 0.11 | 7.34 ± 0.09 | 7.37 ± 0.08 | 7.46 ± 0.10 |
| Hemoglobin (g dL−1) | 16.28 ± 0.18 | 16.36 ± 0.17 | 16.29 ± 0.14 | 16.47 ± 0.17 | 17.97 ± 0.24 | 17.72 ± 0.18 | 17.48 ± 0.16 | 17.59 ± 0.23 |
| Hematocrit (%) | 41.17 ± 0.25 | 42.93 ± 0.21 | 43.29 ± 0.19 | 43.14 ± 0.21 | 42.53 ± 0.26 | 40.28 ± 0.31 | 40.51 ± 0.29 | 40.94 ± 0.23 |
| MCV (fL) | 52.14 ± 0.32 | 52.26 ± 0.28 | 50.13 ± 0.29 | 51.97 ± 0.32 | 50.35 ± 0.29 | 51.91 ± 0.25 | 52.76 ± 0.27 | 49.55 ± 0.23 |
| MCH (pg) | 18.86 ± 0.13 | 19.49 ± 0.19 | 20.56 ± 0.12 | 19.43 ± 0.12 | 19.85 ± 0.19 | 19.81 ± 0.18 | 19.78 ± 0.16 | 19.31 ± 0.17 |
| MCHC (g dL−1) | 35.43 ± 0.31 | 35.62 ± 0.42 | 35.57 ± 0.38 | 35.76 ± 0.29 | 35.30 ± 0.25 | 36.07 ± 0.33 | 36.04 ± 0.27 | 36.01 ± 0.27 |
| RDW (%) | 12.12 ± 0.15 | 12.15± 0.16 | 12.16 ± 0.14 | 12.15 ± 0.17 | 17.04 ± 0.13 | 17.10 ± 0.12 | 17.55 ± 0.13 | 17.57 ± 0.17 |
| Platelets (103 μL−1) | 647.54 ± 26.98 | 626.31 ± 25.23 | 665.08 ± 28.80 | 642.08 ± 32.44 | 679.54 ± 37.73 | 611.85 ± 39.58 | 619.09 ± 25.29 | 606.15 ± 28.31 |
| MPV (fL) | 6.08 ± 0.18 | 5.90 ± 0.08 | 5.89 ± 0.06 | 5.88 ± 0.08 | 5.48 ± 0.09 | 5.21 ± 0.08 | 5.29 ± 0.10 | 5.29 ± 0.07 |
Wistar rats (n = 10 per group) were administered ZZEE by daily gavage for 4 weeks. Data are expressed as mean ± SD.