Table 4.

Effects of subchronic oral administration of the ethanol extract of Z. zerumbet rhizomes (EEZZ) on organ weights of female Wistar rats.

Organs	Organ weight (g)				Relative organ weight (g 100 g−1 of body weight)
	Vehicle	EEZZ (mg kg−1 per day)			Vehicle	EEZZ (mg kg−1 per day)
		1000	2000	3000		1000	2000	3000
Spleen	0.445 ± 0.028	0.436 ± 0.031	0.456 ± 0.027	0.454 ± 0.027	0.182 ± 0.011	0.178 ± 0.018	0.184 ± 0.013	0.186 ± 0.012
Brain	1.111 ± 0.026	1.124 ± 0.030	1.097 ± 0.027	1.116 ± 0.031	0.454 ± 0.019	0.458 ± 0.015	0.443 ± 0.014	0.458 ± 0.016
Heart	0.853 ± 0.018	0.847 ± 0.023	0.825 ± 0.025	0.860 ± 0.019	0.349 ± 0.014	0.345 ± 0.017	0.333 ± 0.011	0.353 ± 0.009
Esophagus	0.093 ± 0.002	0.088 ± 0.003	0.093 ± 0.003	0.093 ± 0.002	0.038 ± 0.003	0.036 ± 0.002	0.038 ± 0.002	0.039 ± 0.004
Stomach	1.385 ± 0.027	1.369 ± 0.026	1.371 ± 0.031	1.379 ± 0.029	0.566 ± 0.013	0.558 ± 0.017	0.553 ± 0.015	0.566 ± 0.016
Liver	8.631 ± 0.048	8.633 ± 0.052	8.523 ± 0.046	8.651 ± 0.061	3.527 ± 0.017	3.520 ± 0.022	3.441 ± 0.019	3.548 ± 0.021
Adrenal gland	0.023 ± 0.002	0.025 ± 0.001	0.026 ± 0.002	0.029 ± 0.002	0.009 ± 0.001	0.010 ± 0.002	0.010 ± 0.003	0.011 ± 0.002
Hypophysis	0.004 ± 0.002	0.004 ± 0.001	0.004 ± 0.001	0.004 ± 0.001	0.001 ± 0.001	0.001 ± 0.001	0.001 ± 0.001	0.001 ± 0.001
Hypothalamus	0.027 ± 0.002	0.028 ± 0.001	0.029 ± 0.001	0.027 ± 0.002	0.011 ± 0.003	0.011 ± 0.002	0.011 ± 0.001	0.012 ± 0.003
Small intestine	0.516 ± 0.021	0.525 ± 0.018	0.515 ± 0.019	0.521 ± 0.022	0.211 ± 0.009	0.214 ± 0.008	0.208 ± 0.007	0.214 ± 0.009
Lungs	1.309 ± 0.053	1.278 ± 0.046	1.308 ± 0.055	1.320 ± 0.043	0.535 ± 0.017	0.521 ± 0.014	0.528 ± 0.019	0.541 ± 0.022
Kidney	0.859 ± 0.029	0.867 ± 0.034	0.874 ± 0.045	0.864 ± 0.037	0.351 ± 0.018	0.354 ± 0.019	0.353 ± 0.017	0.355 ± 0.020
Ovary	0.044 ± 0.003	0.043 ± 0.003	0.042 ± 0.002	0.042 ± 0.002	0.018 ± 0.002	0.017 ± 0.002	0.017 ± 0.003	0.017 ± 0.002
Uterus	0.546 ± 0.026	0.566 ± 0.029	0.574 ± 0.031	0.551 ± 0.039	0.223 ± 0.022	0.230 ± 0.026	0.231 ± 0.025	0.226 ± 0.025

Wistar rats (n = 10 per group) were administered EEZZ by daily gavage for 4 weeks. Data are expressed as mean ± SD.