System designed for the quantitative measurement of analyte levels in a drop of blood. A small device fabricated from paper patterned with wax, a filter membrane, and a plastic sheath processes and analyzes a drop of blood from a fingerstick. The multifunctional device, encased in two self-adhesive laminating sheets, uses the paper to store the reagents for the assays, and the filter on top of the paper to separate plasma from the red blood cells. A cell phone or desktop scanner digitizes the results from the assays, which can be analyzed off-site by trained personnel. Incineration of the devices easily disposes the bio-hazardous waste.