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. 2012 Feb 7;153(4):1887–1897. doi: 10.1210/en.2011-1701

Fig. 4.

Fig. 4.

KP-54 release in vivo from the S-ME/MBH in OVX prepubertal (A and B) and pubertal (C and D) monkeys. Samplings during the morning and evening are shown by open and closed bars, respectively, at the top of each graph. Note that the scale of the y-axis in C and D (pubertal monkeys) is 10-fold higher than that in A and B (prepubertal monkeys). KP-54 release in both prepubertal and pubertal monkeys occurs in a pulsatile manner. The IPI in OVX prepubertal monkeys is longer and the pulse amplitude is lower compared with OVX pubertal monkeys. Asterisks indicate peaks as determined by PULSAR.