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. 2012 Feb 7;153(4):1887–1897. doi: 10.1210/en.2011-1701

Fig. 6.

Fig. 6.

Analysis of KP-54 pulse parameters (A, mean release; B, IPI; and C, pulse amplitude) in OVX prepubertal and pubertal monkeys injected with E2. Note that before E2 injection, the mean KP-54 release, IPI, and pulse amplitude in OVX prepubertal or pubertal monkeys were similar to that in OVX prepubertal or pubertal monkeys shown in Fig. 3, B, D, and F, respectively. E2 injection clearly suppressed mean KP-54 release and pulse amplitude in OVX pubertal monkeys, whereas E2 caused no significant changes in OVX prepubertal monkeys.*, P < 0.05 and **, P < 0.01 vs. prepubertal; b, P < 0.05 vs. before E2 injection; +, P < 0.05 vs. ovarian-intact monkeys. Data obtained before (open bars) and after (shaded bars) E2 injection in prepubertal (n = 3) and pubertal (n = 7) monkeys are shown. Data are mean ± sem.