Table 2. Unique hemagglutinin amino acid substitutions from influenza virus isolates obtained during July 2004 influenza outbreak in southeast Nepal compared with 5 vaccine strains*.

Virus strain	Amino acid position
	145 Glycosylation site adjacent to antibody site A	155 Fujian-like lineage amino acid substitution	156 Fujian-like lineage amino acid substitution	189 Antibody site B	226 Antibody site D	227 Antibody site D
A/Nepal Consensus/04†	N	T	H	N	I	P
A/Fujian/411/02	K	T	H	S	V	S
A/Wyoming/3/03	K	T	H	S	I	S
A/Wellington/1/04	K	T	H	N	V	P
A/California/7/04	N	T	H	N	I	P
A/Panama/2007/99	K	H	Q	S	V	S

*N, asparagine; T, threonine; H, histidine; I, isoleucine; P, proline; K, lysine; S, serine; V, valine; Q, glutamine.
†Consensus sequence derived from a multiple sequence protein alignment of 26 HA1 hemagglutinin sequences from Nepal.