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(a) The genetic map of the region of the MASP2 gene on chromosome 1p36.3-p36.2 is shown (a). The SNPs genotyped in this study are marked above the exons. (b) The polypeptide chain of MASP2 is composed of an N-terminal CUB domain, followed by en EGF domain, a second CUB domain, two CCP (complement-control protein) domains, an activation peptide, and a serine protease domain
