Table 1.
Genes selected for genotyping.
| HUGO Gene Symbol | Gene name | SNPs genotyped | SNPs analysed for association |
|---|---|---|---|
| MBL2 | mannose-binding lectin 2 | 5 | 3 |
| MASP1 | mannan-binding lectin serine peptidase 1 | 8 | 7 |
| MASP2 | mannan-binding lectin serine peptidase 2 | 11 | 10 |
| FCN1 | ficolin 1 | 9 | 7 |
| FCN2 | ficolin 2 | 9 | 9 |
| FCN3 | ficolin 3 | 3 | 1 |
| SERPING1 | serpin peptidase inhibitor (C1 inhibitor) | 5 | 4 |
| C3 | complement component 3 | 7 | 5 |
| CFB | complement factor B | 5 | 5 |
| CFH | complement factor H | 8 | 6 |
| CFP | complement factor properdin | 6 | 3 |
| THBD | thrombomodulin | 5 | 1 |
| THBS1 | thrombospondin 1 | 4 | 3 |
| THBS2 | thrombospondin 2 | 4 | 4 |
| THBS3 | thrombospondin 3 | 2 | 2 |
| THBS4 | thrombospondin 4 | 2 | 2 |
| FLT1 | fms-related tyrosine kinase 1 | 5 | 4 |
| Total number of SNPs | 98 | 76 |
22 SNPs were excluded from genetic association analyses because of low minor allele frequency, poor genotyping quality, or lack of accordance with Hardy-Weinberg equilibrium. Gene symbols and names are given as defined in the HUGO Gene Nomenclature Committee's database