Table 2.
Associations between nuclear and cytoplasmic pERK expression and clinicopathological parameters in 45 patients with colorectal carcinoma.
| pERK nuclear LI | pERK cytoplasmic LI | ||||||
|---|---|---|---|---|---|---|---|
| N | Median | Range | P value | Median | Range | P value | |
| Gender | |||||||
| Male | 24 | 1 | 0-15 | 0 | 0-10 | ||
| Female | 21 | 1 | 0-20 | 0.6999 | 0 | 0-15 | 0.9518 |
| Histological grade | |||||||
| I | 4 | 0 | 0-0 | 0 | 0-0 | ||
| II/III | 41 | 1 | 0-20 | 0.0113 | 0 | 0-15 | 0.2504 |
| TNM stage | |||||||
| I | 5 | 0 | 0-10 | 0 | 0-0 | ||
| II-IV | 40 | 0-20 | 0.0952 | 0 | 0-15 | 0.1873 | |
| Tumor location | |||||||
| Right colon | 33 | 1 | 0-20 | 1 | 0-20 | ||
| Left colon | 12 | 1 | 0-10 | 0.3941 | 5 | 0-10 | 0.4452 |
| Age (years) | 45 | R = 0.3941, p = 0.5687 | R = 0.3153, p = 0.1529 | ||||
Results of Mann Whitney U test.