Fig 3 Predicted absolute risk reduction in mortality by adherence to lung protective ventilation. Estimates based on Cox proportional hazards regression model with time varying covariates used to predict survival estimates for a prototypical patient with eight eligible mechanical ventilator settings with 0% versus 50% or 0% versus 100% adherence to lung protective ventilation. The prototypical patient was presumed to survive for at least four days of eligible ventilation and had median values for all continuous covariates and mode values for binary covariates. Confidence intervals were generated using 500 bootstrap samples