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. 2012 Apr 5;8(4):e1002464. doi: 10.1371/journal.pcbi.1002464

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Sakarya et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Scatterplots show the increasing mapped coverage (x-axis) versus Left: Known RefSeq junctions; Middle: Putative junctions; Right: Fusion junctions. Top track shows results for UHR and bottom track for HBR. Three different evidence thresholds were compared: 1) red line: one SPAN (SR) evidence required for junction call, 2) magenta line: two SPAN (2-SR) evidences required for junction call, and 3) blue line: one SPAN and one BRIDGE evidence (1-SR-1-PE) required for junction call.