Table 2. Validated MCF-7 gene fusions and TaqMan expression ratios.
5′ Gene Exon | Chr | 3′ Gene Exon | Chr | Distance | MCF-7 | UHR | HBR | PC-3 |
ARFGEF2-1 | 20 | SULF2-3 | 20 | Inverted | 20.6 | 24.2 | 40.0 | 39.7 |
SLC25A24-4 | 1 | NBPF6-16 | 1 | Inverted | 23.9 | 27.9 | 40.0 | 40.0 |
USP31-1 | 16 | CRYL1-4 | 13 | Inter-chr | 27.5 | 31.8 | 40.0 | 40.0 |
TBL1XR1-1 | 3 | RGS17-2 | 6 | Inter-chr | 26.1 | 30.6 | 40.0 | 40.0 |
TAF4-1 | 20 | BRIP1-5 | 17 | Inter-chr | 25.6 | 29.2 | 40.0 | 40.0 |
RPS6KB1-6 | 17 | DIAPH3-30 | 13 | Inter-chr | 22.6 | 26.1 | 40.0 | 36.7 |
BCAS4-1 | 20 | BCAS3-24 | 17 | Inter-chr | 21.3 | 25.3 | 40.0 | 40.0 |
AHCYL1-1 | 1 | RAD51C-10 | 17 | Inter-chr | 31.0 | 34.8 | 40.0 | 40.0 |
ABCA5-4 | 17 | PPP4R1L-4 | 20 | Inter-chr | 26.1 | 29.9 | 40.0 | 40.0 |
C16orf45-1 | 16 | ABCC1-15 | 16 | 641567 | 25.3 | 29.2 | 40.0 | 40.0 |
C16orf62-8 | 16 | IQCK-10 | 16 | 264613 | 26.7 | 30.5 | 40.0 | 40.0 |
CXorf15-1 | X | SYAP1-2 | X | −51362 | 29.1 | 32.7 | 40.0 | 40.0 |
MYO6-1 | 6 | SENP6-15 | 6 | −70841 | 28.4 | 31.9 | 40.0 | 40.0 |
RPS6KB1-2 | 17 | TMEM49-11 | 17 | −72316 | 24.4 | 28.4 | 40.0 | 39.8 |
SMARCA4-7 | 19 | CARM1-2 | 19 | −81642 | 29.9 | 33.1 | 40.0 | 40.0 |
POP1-2 | 8 | MATN2-15 | 8 | −86928 | 28.5 | 31.8 | 40.0 | 40.0 |
GATAD2B-1 | 1 | NUP210L-28 | 1 | −107321 | 28.3 | 32.4 | 40.0 | 40.0 |
ESR1-2 | 6 | C6orf97-7 | 6 | −116116 | 32.3 | 35.0 | 40.0 | 40.0 |
ESR1-2 | 6 | C6orf97-6 | 6 | −128831 | 25.2 | 29.1 | 40.0 | 40.0 |
DEPDC1B-7 | 5 | ELOVL7-8 | 5 | −118895 | 25.6 | 29.0 | 39.8 | 40.0 |
GCN1L1-2 | 12 | MSI1-12 | 12 | −157216 | 25.3 | 28.2 | 40.0 | 39.8 |
ATXN7L3-1 | 17 | FAM171A2-4 | 17 | −158568 | 24.8 | 28.3 | 40.0 | 40.0 |
SYTL2-1 | 11 | PICALM-20 | 11 | −217187 | 26.7 | 30.7 | 40.0 | 40.0 |
ADAMTS19-1 | 5 | SLC27A6-10 | 5 | −432137 | 26.5 | 31.3 | 40.0 | 40.0 |
ADAMTS19-2 | 5 | SLC27A6-10 | 5 | −433412 | 25.8 | 30.5 | 40.0 | 40.0 |
Notes: Each exon name (gene name-dash-exon-order) was obtained from RefSeq database. Inverted fusions are on same chromosome but different strands. Last four columns show the Cycle Threshold (CT) value in TaqMan assays. Lower CT values indicate higher expression.