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. 2012 Apr 5;7(4):e35244. doi: 10.1371/journal.pone.0035244

Figure 4. Excitable properties of MNIM-treated EOH cells.

Figure 4

Representative perforated patch clamp recordings from uninduced EOH cells (A) or MNIM-EOH cells (B). The cells were held at −60 mV and currents elicited by stepping from −90 to +30 mV in 10 mV steps. MNIM-EOH cells express robust outward K+ currents but very small inward Na+ currents (filled upright triangle). Current injection (200 pA, 100 ms) induced action potential in MNIM-EOH cells, not in uninduced EOH cells. (C) Resting membrane potential in uninduced EOH cells and MNIM-EOH cells. The bars represent mean ± SEM. * P<0.05. The significance was determined by Student’s t test.