Table 6.

SAR around hit series 2 b.

Compd	R2	R1	R	TbTryS IC50 [μm]
43	H	H	H	>50
44	H	2-CH3	H	15
45	H	2-Cl	H	25
46	H	H	2,5-di-Cl	16
47	H	H	4-NHCOCH3	5.9
48	H	H	4-OCH3	11
49	H	2-CH3	4-OCH3	4.0
50	H	2-CH3	4-NHCOCH3	1.7
51	H	2-Cl	4-NHCOCH3	3.7
52	CH3	H	4-NHCOCH3	>50