Table 1.
entry | Pd catalyst | initial rate (M/s)a |
---|---|---|
1 | 2 (1 mol%), Pd(PtBu3)2 (5 mol%) | 2.8 × 10−6 |
2 | 2 (2 mol%), Pd(PtBu3)2 (5 mol%) | 5.3 × 10−6 |
3 | 2 (5 mol%), Pd(PtBu3)2 (5 mol%) | 8.5 × 10−6 |
4 | 2 (5 mol%), Pd(PtBu3)2 (2 mol%) | 7.7 × 10−6 |
5 | 2 (5 mol%), Pd(PtBu3)2 (1 mol%) | 8.2 × 10−6 |
Calculated by monitoring the reaction by GC during the first hour (estimated errors are ±0.3 X 10−6 M/s)