Table 3.

HDL Particle Subclasses by Treatment Group

	DC Median Change (IQR)	VS Median Change (IQR)	VS-DC % difference* (95%CI)	p-value
Total HDL-P (nmol/L)
2 Months	0.0 (−2.5, 2.8)	1.8 (−1.5, 5.2)	11.8 (4.6–19.5)	0.001
6 Months	0.4 (−3.0, 2.3)	2.2 (−1.7, 6.4)	12.9 (7.1–19.1)	<0.001
Large HDL-P (nmol/L)
2 Months	0.1 (−1.0, 1.1)	1.0 (−0.5, 2.6)	16.7 (1.8–33.8)	0.03
6 Months	0.0 (−1.4, 1.0)	1.0 (0.0, 2.5)	28.7 (10.8–49.5)	0.001
Medium HDL-P (nmol/L)
2 Months	0.0 (−0.9, 1.4)	0.3 (−1.9, 2.7)	16.3 (−25.5–81.7)	0.51
6 Months	0.3 (−0.9, 2.1)	0.9 (−1.4, 3.2)	72.2 (12.0–164.9)	0.01
Small HDL-P (nmol/L)
2 Months	−0.6 (−3.5, 2.8)	0.4 (−3.0, 3.6)	6.2 (−5.9–19.8)	0.33
6 Months	−0.2 (−3.3, 2.2)	0.9 (−3.4, 4.8)	6.2 (−3.8–17.2)	0.24

^*Difference is adjusted for baseline level of corresponding HDL-P measure, and, thus, represents the change in these lipoprotein measures attributable to starting ART