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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: Neuroimage. 2012 Jan 25;60(3):1622–1629. doi: 10.1016/j.neuroimage.2012.01.075

Table 1.

Baseline features of patients with MCI (converters and non-converters to AD) and healthy control participants.

Feature Patients with MCI Healthy
Controls		 *P< Amnestic
MCI
    31
Converters		 99
Non-converters		     61
controls		 94 patients
Gender % female 56.8 55.6 54.8 .99 55.3
Baseline Age in years,
mean ±SD 		73.2 ± 7.0 65.2 ± 10 66.2 ± 9.3 .001 67.7 ± 9.5
Education in years,
mean ±SD 		13.7 ± 5.0 15.3 ± 4.2 16.7 ± 2.6 .002 14 ± 5
Baseline MMSE,
mean ± SD 		26.3 ± 2.2 28.0 ± 2.0 29.3 ± 0.8 .0001 27.0 ± 2
Apolipoprotein E ε4 carrier % 39 24 21 .18 0 ± 1
+Follow-up duration in years 2.2 ± 1.7 4.68 ± 2.37 5.34 ± 2.50 .001 3.91 ± 2.58
**Hippocampal volume (R+L) 3.75 ± 0.72 4.40 ± 0.57 4.35 ± 0.56 .001 4.15 ± 0.60
**Parahippocampal gyrus
volume (R+L) 		5.80 ± 1.17 6.67 ± 0.94 6.70 ± 1.0 .001 6.31 ± 1.06
**Entorhinal cortex volume
(R+L) 		0.37 ± 0.08 0.46 ± 0.08 0.55 ± 0.10 .001 0.44 ± 0.09
Supratentorial intracranial
volume in cc 		1287 ± 117 1306 ± 127 1316 ± 131 .57 1294 ± 127

All values are means ± standard deviations, or percentages.

MMSE: 30-item Folstein Mini-Mental State Exam.

*

P: P value in ANOVA and ANCOVA comparison of MCI converters, non-converters, and healthy controls.

+

Converters to AD exited the study after 2 consecutive annual AD diagnoses, thereby reducing the follow-up duration in this group.

*

Significance level for χ2 or ANOVA (ANCOVA for hippocampal, parahippocampal gyrus and entorhinal cortex volumes, covarying for age, education and intracranial volume).

**

Hippocampal, parahippocampal gyrus and entorhinal cortex volumes are in cubic cm. In ANCOVAs, hippocampal and parahippocampal gyrus and entorhinal cortex volumes were analyzed for converters/non-converters/controls restricted to the 3-year follow-up sample, covarying for intracranial volume.