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. Author manuscript; available in PMC: 2012 Apr 6.
Published in final edited form as: Chem Biol Drug Des. 2010 Nov 29;77(1):39–47. doi: 10.1111/j.1747-0285.2010.01052.x

Figure 5.

Figure 5

Differences in backbone amide chemical shift of the RNH fragment in the presence or absence of four-fold BHMP07 recorded in the absence (A) or presence (B) of 20 mM Mg2+. The BHMP07-induced shift in the RNH was calculated as the square root of the sum of the square of the 1H and 15N chemical shift difference. The resonances were considered shifted when the difference was greater than 20 Hz, based on resolution and signal broadenings. The region inserted from E. Coli RNH is indicated by a solid-line arrow (residues 81 to 103) and the “substrate handle region” is indicated by a dashed arrow (residues 72 to 110).