Skip to main content
. Author manuscript; available in PMC: 2012 Apr 6.
Published in final edited form as: Chem Biol Drug Des. 2010 Nov 29;77(1):39–47. doi: 10.1111/j.1747-0285.2010.01052.x

Table 1.

Inhibitory properties of acylhydrazones used in the present study

PROPERTY graphic file with name nihms349493u1.jpg graphic file with name nihms349493u2.jpg graphic file with name nihms349493u3.jpg
DHBNHa BHMP03 BHMP07
Inhibition of RT DNA polymerase activity (IC50, μM) > 25 > 50 0.3 ± 0.2
Inhibition of RT RNH (IC50, μM) 0.5 ± 0.2 0.4 ± 0.2 0.2 ± 0.1
Inhibition of the p15-EC RNH fragment (IC50, μM) 18.5 ± 3.4 > 50 0.8 ± 0.06
a

Data were taken from the reference, (20). Enzyme activity was measured as described in Materials and Methods.