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Localization and conservation of in vitro selected CNCs. mVISTA plot comparing the human reference sequence with orthologous sequences from 5 vertebrates (window shown 215 kb). Orange-highlighted regions designate CNC sequences that were capable of driving luciferase 2-fold compared with the control plasmid (see Figure 1). Colored peaks indicate sequence conservation of 70% identity across 100 nucleotides (red, noncoding; blue, exons).
