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. 2010 Nov 30;117(4):1408–1414. doi: 10.1182/blood-2010-07-299099

Table 1.

Effects of sBD1 on thrombus size and TF expression in murine macrophages induced by IgG-APS

Treatments Thrombus size, μm2 TF expression in macrophages, AU
IgG-APS 4094.4 ± 1036.8* 10.1 ± 1.4
IgG-NHS 287.4 ± 110.0 3.2 ± 0.5
IgG-APS + sBD1 665.0 ± 173.0 4.4 ± 0.6
IgG-NHS + sBD1 486.0 ± 164.0 3.2 ± 0.7
Dimer 3757 ± 162 13.4 ± 3.7§
Monomer 552.0 ± 79.6 3.4 ± 0.8
Dimer + sBD1 533 ± 148 6.9 ± 1.5
Monomer + sBD1 552.0 ± 133.0 4.9 ± 1.2

AU indicates arbitrary unit; IgG-APS, immunoglobulin G from a patient with antiphospholipid syndrome; IgG-NHS, immunoglobulin G from a patient with normal human serum; sBD1, soluble binding domain 1 of ApoER2; and TF, tissue factor.

Statistically significant from their controls and from sBD1-treated mice; IgG-APS (*P < .0001) and †(P < .0001) or dimer (‡P = .0044) and (§P = .0001).