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. Author manuscript; available in PMC: 2012 Apr 9.
Published in final edited form as: Am J Epidemiol. 2010 Nov 17;173(1):26–37. doi: 10.1093/aje/kwq319

Table 5.

In situ Breast Cancers: Hazard Ratios and Relative Indices of Inequality by Education Among all Women and Among Nulliparous, Parous, Premenopausal and Postmenopausal EPIC Women After Adjustment for Reproductive History and all Risk Factors Together.

Model adjusted for RII 95% CI Primary Vocational secondary Other secondary University or post-secondary vocational
HR HR 95% CI HR 95% CI HR 95% CI
All women
Model 0: Stratified for age and center a 1.86 1.28, 2.70 1 0.94 0.71, 1.24 1.24 0.91, 1.70 1.57 1.18, 2.08
Model 0 + Reproductive historyb 1.70 1.15, 2.51 1 0.92 0.69, 1.21 1.20 0.87, 1.65 1.47 1.10, 1.97
Model 0 + All risk factorsc 1.61 1.07, 2.41 1 0.89 0.67, 1.18 1.15 0.83, 1.59 1.40 1.03, 1.90
Nulliparous women
Model 0: Stratified for age and center a 3.92 1.38, 11.1 1 1.46 0.48, 2.78 1.39 0.53, 3.63 2.55 1.17, 5.55
Model 0 + All risk factorsd 4.53 1.50, 13.7 1 1.08 0.44, 2.64 1.45 0.54, 3.86 2.68 1.18, 6.08
Parous women
Model 0: Stratified for age and center a 1.68 1.11, 2.53 1 0.93 0.69, 1.24 1.28 0.92, 1.79 1.44 1.05, 1.97
Model 0 + Reproductive history 1.52 0.99, 2.32 1 0.90 0.67, 1.22 1.23 0.87, 1.72 1.33 0.96, 1.84
Model 0 + All risk factorsc 1.39 0.89, 2.17 1 0.87 0.64, 1.17 1.16 0.82, 1.64 1.25 0.89, 1.75
Premenopausal women
Model 0: Stratified for age and center a 2.98 1.37, 6.47 1 1.97 1.03, 3.78 1.89 0.96, 3.71 2.70 1.46, 4.98
Model 0 + Reproductive history 2.92 1.28, 6.68 1 1.98 1.02, 3.81 1.92 0.97, 3.82 2.68 1.41, 5.10
Model 0 + All risk factorse 2.68 1.13, 6.34 1 1.90 0.97, 3.71 1.90 0.94, 3.83 2.51 1.28, 4.93
Postmenopausal women
Model 0: Stratified for age and center a 1.26 0.76, 2.10 1 0.70 0.49, 1.00 1.14 0.76, 1.71 1.16 0.78, 1.71
Model 0 + Reproductive history 1.09 0.65, 1.84 1 0.67 0.47, 0.96 1.05 0.70, 1.59 1.03 0.69, 1.55
Model 0 + All risk factorsf 0.94 0.55, 1.64 1 0.62 0.43, 0.90 0.96 0.63, 1.46 0.93 0.61, 1.42

CI confidence interval; HR hazard ratio; RII relative index of inequality;

a

Model 0 controls for age at baseline (1-year age category) and center;

b

Reproductive history: variable combining parity and age at first full term pregnancy;

c

reproductive history, ever breast feeding, common risk factors g, ever use of hormonal replacement therapy, menopausal status&age at menopause combined;

d

common risk factors g, ever use of hormonal replacement therapy, menopausal status&age at menopause combined;

e

reproductive history, ever breast feeding, common risk factors g;

f

reproductive history, ever breast feeding, common risk factors g, ever use of hormonal replacement therapy, age at menopause;

g

Common risk factors: age at menarche, ever use of oral contraceptives, height, BMI, alcohol consumption, total physical activity.