FIGURE 6.

Expression of miR-130a and AQP4 M1 in astrocytoma cells subjected to 6 h of hypoxia or OGD. Total cellular RNA was extracted and used to quantify miR-130a and AQP4 M1 levels. Up-regulation AQP4 M1 mRNA under hypoxic and OGD conditions with a relative decrease in miR-130a expression was observed. All values were expressed relative to negative controls. Statistical analyses were done using t tests. *, p < 0.05; **, p < 0.01 compared with control. Error bars represent the mean ± S.E. (n = 3).