TABLE 1.
Blood constituents | NDa |
FFHC |
HFHC |
Fast |
||||
---|---|---|---|---|---|---|---|---|
WT | Mut | WT | Mut | WT | Mut | WT | Mut | |
Glu (mg/dl) | 205 ± 23 | 182 ± 9 | 151 ± 10 | 151 ± 9 | 233 ± 19 | 186 ± 13b | 74 ± 13 | 71 ± 11 |
Cholesterol (mg/dl) | 145 ± 22 | 154 ± 22 | 92 ± 15 | 123 ± 9b | 204 ± 38 | 270 ± 26 | 177 ± 11 | 149 ± 10b |
HDL cholesterol (mg/dl) | 131 ± 33 | 140 ± 22 | 83 ± 10 | 104 ± 6b | 186 ± 31 | 242 ± 35b | 165 ± 11 | 145 ± 10 |
LDL cholesterol (mg/dl) | 14 ± 2 | 18 ± 3 | 12 ± 11 | 21 ± 4b | 17 ± 4 | 29 ± 7b | 12 ± 2 | 11 ± 3 |
TG (mg/dl) | 157 ± 52 | 101 ± 15b | 91 ± 20 | 61 ± 4b | 137 ± 41 | 93 ± 15b | 160 ± 40 | 80 ± 6b |
VLDL cholesterol (mg/dl) | 32 ± 11 | 20 ± 9b | 18 ± 4 | 12 ± 1b | 28 ± 8 | 18 ± 3b | 38 ± 12 | 16 ± 1b |
NEFA (mEq/dl) | 3.1 ± 0.3 | 2.3 ± 0.2b | 1.1 ± 0.1 | 0.8 ± 0.1 | 2.1 ± 0.4 | 1.5 ± 0.2b | 1.7 ± 0.1 | 1.2 ± 0.1b |
a ND, normal diet; FFHC, fasted-refed; Fast, fasted for 48 h; HFHC, high-fat, high-carbohydrate diet; mut, mutant; NEFA: nonesterified fatty acids; VLDL, very low-density lipoprotein.
b Values are mean ± S.D. (n = 5), p < 0.05.