Table 2. Growth plate characteristics of rats treated with vehicle (C), rapamycin (RAPA) or with rapamycin and growth hormone (RGH).
C (n = 10) | RAPA (n = 10) | RGH (n = 10) | |
Epiphyseal cartilage height (µm) | 396±27 | 471±10a | 579±40a,b |
Hypertrophic zone height (µm) | 232±21 | 271±11a | 345±28a,b |
Terminal chondrocyte height (µm) | 26±1 | 25±0 | 27±1b |
Values are expressed as mean±SEM.
Means statistically different from C group (P≤0.05).
Means statistically different from RAPA group (P≤0.05).