Table 1.
All | 65-74 years of age | >=75 years of age | P value of >=75 vs. 65-74 smokers* | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Never smokers | Smokers | Never smokers | Smokers | Never smokers | Smokers | ||||||
(n = 1094) | (n = 148) | P value* | (n = 641) | (n = 110) | P value* | (n = 453) | (n = 38) | P value* | |||
Baseline covariates | |||||||||||
Female | 668 (61.1%) | 91 (61.5%) | >0.99 | 379 (59.1%) | 66 (60.0%) | 0.92 | 289 (63.8%) | 25 (65.8%) | 0.86 | 0.57 | |
Education ? high school | 674 (61.6%) | 86 (58.1%) | 0.42 | 457 (71.3%) | 66 (60.0%) | 0.02 | 217 (47.9%) | 20 (52.6%) | 0.62 | 0.45 | |
Use 3 or more prescription drugs | 350 (32.0%) | 45 (30.4%) | 0.78 | 164 (25.6%) | 32 (29.1%) | 0.48 | 186 (41.1%) | 13 (34.2%) | 0.49 | 0.55 | |
Lipid-lowering drug use | 32 (2.9%) | 1 (0.7%) | 0.17 | 26 (4.1%) | 1 (0.9%) | 0.16 | 6 (1.3%) | 0 (0.0%) | >0.99 | >0.99 | |
NSAID use | 753 (68.8%) | 101 (68.2%) | 0.93 | 446 (69.6%) | 79 (71.8%) | 0.74 | 307 (67.8%) | 22 (57.9%) | 0.21 | 0.16 | |
>5 depressive symptoms | 98 (9.0%) | 23 (15.9%) | 0.02 | 45 (7.1%) | 17 (15.6%) | 0.01 | 53 (11.8%) | 6 (16.7%) | 0.42 | >0.99 | |
Self-reported health poor** | 19 (1.7%) | 7 (4.7%) | 0.03 | 7 (1.1%) | 4 (3.6%) | 0.06 | 12 (2.7%) | 3 (7.9%) | 0.10 | 0.37 | |
# of alcoholic drinks at a time per day: | none | 507 (46.4%) | 56 (37.8%) | <0.001 | 265 (41.4%) | 38 (34.6%) | <0.001 | 242 (53.4%) | 18 (47.4%) | 0.07 | 0.18 |
1/day | 402 (36.8%) | 41 (27.7%) | 247 (38.6%) | 31 (28.2%) | 155 (34.2%) | 10 (26.3%) | >0.99 | ||||
2+/day | 184 (16.8%) | 51 (34.5%) | 128 (20.0%) | 41 (37.3%) | 56 (12.4%) | 10 (26.3%) | 0.24 | ||||
APOE ε4 allele | 164/1488 (11.0%) | 23/190 (12.1%) | 0.63 | 120/956 (12.6%) | 18/160 (11.3%) | 0.70 | 44/532 (8.3%) | 5/30 (16.7%) | 0.17 | 0.37 | |
Vascular risk factors | |||||||||||
History of stroke | 30 (3.2%) | 2 (1.6%) | 0.57 | 12 (2.2%) | 1 (1.1%) | 0.70 | 18 (4.7%) | 1 (3.5%) | >0.99 | 0.45 | |
History of MI | 123 (13.1%) | 10 (8.1%) | 0.15 | 67 (12.0%) | 9 (9.5%) | 0.60 | 56 (14.6%) | 1 (3.5%) | 0.16 | 0.45 | |
History of diabetes | 122 (13.0%) | 8 (6.5%) | 0.04 | 66 (11.8%) | 5 (5.3%) | 0.07 | 56 (14.6%) | 3 (10.3%) | 0.78 | 0.42 | |
History of hypertension | 436 (46.3%) | 47 (37.9%) | 0.08 | 254 (45.5%) | 33 (34.7%) | 0.06 | 182 (47.5%) | 14 (48.3%) | >0.99 | 0.43 | |
History of high cholesterol | 275 (30.7%) | 27 (24.3%) | 0.19 | 188 (35.5%) | 21 (25.0%) | 0.06 | 87 (23.8%) | 6 (22.2%) | >0.99 | 0.81 |
Based on Fisher’s exact tests.
Compared to fair/good/excellent.