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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Alzheimer Dis Assoc Disord. 2012 Oct;26(4):300–306. doi: 10.1097/WAD.0b013e3182420b6e

Table 1.

Individual characteristics by smoking status and by age at baseline (wave 2).

All 65-74 years of age >=75 years of age P value of >=75 vs. 65-74 smokers*
Never smokers Smokers Never smokers Smokers Never smokers Smokers
(n = 1094) (n = 148) P value* (n = 641) (n = 110) P value* (n = 453) (n = 38) P value*
Baseline covariates
Female 668 (61.1%) 91 (61.5%) >0.99 379 (59.1%) 66 (60.0%) 0.92 289 (63.8%) 25 (65.8%) 0.86 0.57
Education ? high school 674 (61.6%) 86 (58.1%) 0.42 457 (71.3%) 66 (60.0%) 0.02 217 (47.9%) 20 (52.6%) 0.62 0.45
Use 3 or more prescription drugs 350 (32.0%) 45 (30.4%) 0.78 164 (25.6%) 32 (29.1%) 0.48 186 (41.1%) 13 (34.2%) 0.49 0.55
Lipid-lowering drug use 32 (2.9%) 1 (0.7%) 0.17 26 (4.1%) 1 (0.9%) 0.16 6 (1.3%) 0 (0.0%) >0.99 >0.99
NSAID use 753 (68.8%) 101 (68.2%) 0.93 446 (69.6%) 79 (71.8%) 0.74 307 (67.8%) 22 (57.9%) 0.21 0.16
>5 depressive symptoms 98 (9.0%) 23 (15.9%) 0.02 45 (7.1%) 17 (15.6%) 0.01 53 (11.8%) 6 (16.7%) 0.42 >0.99
Self-reported health poor** 19 (1.7%) 7 (4.7%) 0.03 7 (1.1%) 4 (3.6%) 0.06 12 (2.7%) 3 (7.9%) 0.10 0.37
# of alcoholic drinks at a time per day: none 507 (46.4%) 56 (37.8%) <0.001 265 (41.4%) 38 (34.6%) <0.001 242 (53.4%) 18 (47.4%) 0.07 0.18
1/day 402 (36.8%) 41 (27.7%) 247 (38.6%) 31 (28.2%) 155 (34.2%) 10 (26.3%) >0.99
2+/day 184 (16.8%) 51 (34.5%) 128 (20.0%) 41 (37.3%) 56 (12.4%) 10 (26.3%) 0.24
APOE ε4 allele 164/1488 (11.0%) 23/190 (12.1%) 0.63 120/956 (12.6%) 18/160 (11.3%) 0.70 44/532 (8.3%) 5/30 (16.7%) 0.17 0.37
Vascular risk factors
History of stroke 30 (3.2%) 2 (1.6%) 0.57 12 (2.2%) 1 (1.1%) 0.70 18 (4.7%) 1 (3.5%) >0.99 0.45
History of MI 123 (13.1%) 10 (8.1%) 0.15 67 (12.0%) 9 (9.5%) 0.60 56 (14.6%) 1 (3.5%) 0.16 0.45
History of diabetes 122 (13.0%) 8 (6.5%) 0.04 66 (11.8%) 5 (5.3%) 0.07 56 (14.6%) 3 (10.3%) 0.78 0.42
History of hypertension 436 (46.3%) 47 (37.9%) 0.08 254 (45.5%) 33 (34.7%) 0.06 182 (47.5%) 14 (48.3%) >0.99 0.43
History of high cholesterol 275 (30.7%) 27 (24.3%) 0.19 188 (35.5%) 21 (25.0%) 0.06 87 (23.8%) 6 (22.2%) >0.99 0.81
*

Based on Fisher’s exact tests.

**

Compared to fair/good/excellent.