Table 3.
Effect of hysterectomy and time since hysterectomy on odds of oncogenic and non-oncogenic HPV infection in 219 women with hysterectomy at baseline compared to 103 women who only later went on to have a hysterectomy.
| Hysterectomy and time since hysterectomy | Subject-Visits | Oncogenic HPV | Non-Oncogenic HPV | Oncogenic vs. Non-oncogenic& | ||
|---|---|---|---|---|---|---|
| EFFECT ON PREVALENT HPV | OR^ | 95% CI | OR^ | 95% CI | PInteraction | |
| Hysterectomy at baseline | ||||||
| No | 784 | 1.00 | 1.00 | 0.0004 | ||
| Yes | 1982 | 0.41 | 0.25-0.66 | 1.29 | 0.97-1.70 | |
| Time since hysterectomy | ||||||
| No hysterectomy at baseline | 784 | 1.00 | 1.00 | |||
| <5 yrs | 243 | 0.33 | 0.18-0.61 | 1.15 | 0.75-1.75 | |
| 5-14 yrs | 672 | 0.44 | 0.23-0.85 | 1.18 | 0.85-1.64 | 0.006 |
| ≥ 15 yrs | 975 | 0.38 | 0.20-0.70 | 1.59 | 1.14-2.21 | |
| P-trend | P=0.95 | P=0.05 | ||||
| EFFECT ON INCIDENT HPV | Subject-Visits | HR^ | 95% CI | HR^ | 95% CI | PInteraction |
| Hysterectomy at baseline | ||||||
| No | 784 | 1.00 | 1.00 | 0.14 | ||
| Yes | 1982 | 0.64 | 0.39-1.03 | 0.96 | 0.70-1.33 | |
| Time since hysterectomy | ||||||
| No hysterectomy at baseline | 784 | 1.00 | 1.00 | |||
| <5 yrs | 243 | 0.65 | 0.34-1.22 | 0.84 | 0.52-1.37 | 0.30 |
| 5-14 yrs | 672 | 0.57 | 0.31-1.06 | 0.89 | 0.59-1.32 | |
| ≥ 15 years | 975 | 0.61 | 0.33-1.10 | 1.14 | 0.78-1.65 | |
| P-trend | P=0.96 | P=0.14 | ||||