Table 4.
Psychiatric Disorders at Follow-Up by Reflux Esophagitis, Normal Histology, and Control Group
| Reflux Esophagitis (n=50) |
Normal Histology (n=53) |
Controls (n=142) |
p-value Reflux vs. Normal |
p-value Reflux vs. Control |
p-value Normal vs. Control |
|
|---|---|---|---|---|---|---|
| Current | ||||||
| Anxiety Disorder | 28.3% (13/46) |
24.5% (13/53) |
13.6% (19/140) |
NS | <0.05 | NS |
| Mood Disorder | 6.5% (3/46) |
7.5% (4/53) |
2.9% (4/140) |
NA | NA | NA |
| Lifetime | ||||||
| Anxiety Disorder | 43.5% (20/46) |
54.7% (29/53) |
23.6% (33/140) |
NS | <0.05 | <0.001 |
| Mood Disorder | 34.8% (16/46) |
49.1% (26/53) |
20.0% (28/140) |
NS | <0.05 | <0.001 |
Note: Current and Lifetime Anxiety and Mood Disorder criteria based upon The Anxiety Disorders Interview (ADIS), Schedule-IV; GER= gastroesophageal reflux; FD= functional dyspepsia