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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Neurobiol Aging. 2011 Dec 14;33(6):1121.e13–1121.e24. doi: 10.1016/j.neurobiolaging.2011.11.003

Figure 3. Changes in [Ca2+]i in response to K+ depolarization (a-c) or the release of ER calcium stores (d-f).

Figure 3

Calcium homeostasis was evaluated in multiple cell types by assessing the responses of cytosolic free calcium to depolarizing concentrations of K+ (50 mM) in N2a (a), neurons from embryonic mice (b), and neurons from adult mice (c). The release of ER calcium by either bradykinin (200 nM) or caffeine (25 mM) was determined in N2a cells (d), neurons from embryonic mice (e), and neurons from adult mice (f). The gray areas represent the calcium integration between 60 sec to 360 sec above basal. The values represent an average response of 187 to 355 neurons. The error bars represent the standard errors. In most cases they were too small to see.