Figure 8.

SF3a does not bind a rearranged form of SL2a. (A) A schematic diagram showing the region of yeast U2 snRNA having alternative conformations. The stem and loop regions of SL2a are indicated with red and blue letters, respectively. The downstream sequences involved in the formation of stem IIc are shown in green letters. (B) A schematic diagram of the RNA elements, S2c and S2c+L2b, used for binding studies. (C) EMSA results of the binding of the SF3a core complex to S2c and S2c+L2b elements of U2 snRNA, in comparison to that of SL2a.