Table 1. Baseline Demographic, Biochemical, and Histological Data for 102 Patients With Autoimmune Hepatitis. All values are Mean ± SD, otherwise noted.
| Overall | Cirrhotic | Non-Cirrhotic | P value b | |
| Female, No. (%) | 75 (73.5) | 42 (72.4) | 33 (75.0) | 0.77c |
| Age at presentation, y | 29.1 ± 15.3 | 26.5 ± 15.2 | 32.5 ± 14.8 | 0.049 |
| AST a, IU/L | 524.9 ± 428.9 | 540.0 ± 414.4 | 513.9 ± 442.6 | 0.77 |
| ALT a, IU/L | 552.8 ± 480.1 | 605.9 ± 481.5 | 514.7 ± 479.7 | 0.36 |
| Alkaline phosphatase, IU/L | 441.7 ± 285.4 | 444.8 ± 300.1 | 439.3 ± 276.6 | 0.93 |
| Serum γ –globulin, g/dL | 255.4 ± 219.6 | 367.6 ± 252.3 | 172.3 ± 148.1 | 0.002 |
| Total bilirubin, mg/dL | 5.8 ± 6.8 | 7.4 ± 8.4 | 4.6 ± 4.9 | 0.06 |
| Direct bilirubin, mg/dL | 3.7 ± 4.6 | 4.9 ± 5.7 | 2.7 ± 3.2 | 0.02 |
| Total protein, g/dL | 8.2 ± 1.3 | 8.0 ± 1.4 | 8.4 ± 1.1 | 0.32 |
| Albumin, g/dL | 2.5 ± 1.5 | 2.3 ± 1.5 | 2.9 ± 1.6 | 0.08 |
| White blood cell, No./mm3 | 7628 ± 3682 | 8682 ± 4458 | 6848 ± 2781 | 0.06 |
| Hemoglobin, g/dL | 12.6 ± 1.8 | 12.6 ± 1.9 | 12.8 ± 1.6 | 0.65 |
| ESR a | 37.2 ± 31.0 | 33.1 ± 31.6 | 42.3 ± 30.1 | 0.22 |
| Platelet count (× 1000), No./mm3 | 199.5 ± 111.0 | 183.9 ± 121.4 | 220.7 ± 92.5 | 0.14 |
| Prothrombin time, s | 15.6 ± 3.7 | 16.1 ± 2.9 | 14.9 ± 4.6 | 0.16 |
| INR a | 1.7 ± 0.9 | 1.8 ± 0.8 | 1.5 ± 1.2 | 0.28 |
| Blood urea nitrogen, mg/dL | 14.1 ± 7.3 | 15.0 ± 8.4 | 13.3 ± 6.4 | 0.45 |
| Creatinine, mg/dL | 0.8 ± 0.4 | 0.9 ± 0.6 | 0.7 ± 0.3 | 0.09 |
| HAI a | 12.7 ± 3.9 | 14.5 ± 3.1 | 10.9 ± 3.9 | < 0.001 |
| Grade | 9.1 ± 3.1 | 9.8 ± 2.8 | 8.4 ± 3.4 | 0.049 |
| Stage | 3.9 ± 1.3 | 4.8 ± 0.9 | 2.9 ± 1.0 | < 0.001 |
a Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; ESR, erythrocyte sedimentation rate; HAI, hepatitis activity index; INR, international normalized ratio
b P value calculated using t test
c P value calculate using chi square test