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. Author manuscript; available in PMC: 2012 Apr 8.
Published in final edited form as: Sci Transl Med. 2011 May 18;3(83):83ra40. doi: 10.1126/scitranslmed.3002099

Figure 1. Stimulation of CD4+ T cells with allogeneic APC combined with PDE3 inhibition leads to an enrichment of Foxp3+ T cells.

Figure 1

Naive CBA (H-2k) CD25−CD4+ T cells were co-cultured with B6 (H-2b) BM DCs in the presence of the PDE3 inhibitor cilostamide at the concentrations shown. Cells gated on CD4 and TCR-β for analysis of intracellular Foxp3 expression. (A) Representative plots. (B) Quantification.