Table 1.
Distribution of some S. aureus genes among human and animal strains.
Gene | Function | Effect | Presence/absence in isolates from |
Reference | |
---|---|---|---|---|---|
Humans | Animals (species), clone | ||||
spa | FC binding | Impairment of antibody function | P | A° (poultry), ST5 A° (cattle), ST151 |
Lowder et al. (2009), Herron-Olson et al. (2007) |
chp | Chemotaxis inhibitor | Impairment of host native immunity | P | A (poultry), ST5 A (cattle), ST151 |
Lowder et al. (2009), Monecke et al. (2007), Sung et al. (2008) |
scn | Complement inhibitor | Impairment of host native immunity | P | A (poultry), ST5 A (cattle), ST151 |
Lowder et al. (2009), Monecke et al. (2007), Sung et al. (2008) |
sak | Plasminogen activator | Coagulation of plasma | P | A (cattle), ST151 A (poultry, pigs), ST1 |
Lowder et al. (2009), Monecke et al. (2007), Sung et al. (2008), Franco et al. (2011) |
vWbpSov2 | von Willebrand factor-binding (coagulase)^ | Coagulation of plasma | A | P (ruminants), CC133 | Guinane et al. (2010) |
P, present; A, absent.
°Gene disrupted or pseudogene.
^Ruminant variant.