Figure 7.

Assessment of hippocampal CA3 neurons in the brains of vehicle- or EpoD-treated 12-month-old mice PS19. A, B, Low-power representative images of hippocampal NeuN immunostaining from 12-month-old vehicle-treated WT (A) and PS19 (B) mice, with the regions sampled for quantification of 20× images denoted by boxes. C, Quantification of the CA3 NeuN area in WT or PS19 mice treated with vehicle or EpoD at the indicated dose. All data are normalized to the mean area obtained in the vehicle-treated WT mice. Error bars indicate SEM; *p < 0.05, as determined by one-way ANOVA and Tukey's multiple-comparison test, with n = 8–10 mice/group. Veh, Vehicle.