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. 2012 Mar 13;8:574. doi: 10.1038/msb.2012.6

Figure 5.

Figure 5

The effect of TOC1 level on the kinetics of LHY and CCA1 expression. qRT–PCR measurements of CCA1 (A) and LHY (B) mRNA levels, and model simulations of LHY/CCA1 (C) expression in TOC1-ox, toc1 and WT plants under 12L:12D cycles were performed as described in the Supplementary information. TOC1-ox was simulated by adding a constant, unregulated activation of TOC1 transcription with a rate constant equal to 0.3 per hour, which correspond the observed expression level of TOC1 in TOC1-ox (Supplementary Figure S1).