Table II.
MicroRNAs associated with life expectancy on a cohort-independent or-dependent manner and supporting independent studies.
| MicroRNA | P-value | Hazard ratio (95% C.I.) | Relevant literature references |
|---|---|---|---|
| hsa-miR-181a* | 0.0537 | RX=0; 0.33 (0.21 to 0.51) RX=1; 1.05 (0.33 to 3.38) |
(3, 4)G |
| hsa-miR-189 | 0.0204 | 0.20 (0.05 to 0.78) | (45)O |
| hsa-miR-19b | 0.0049 | 1.46 (1.11 to 1.90) | (51)G |
| hsa-miR-222 | 0.0258 | 0.83 (0.70 to 0.98) | (6, 37, 38)G |
| hsa-miR-34a | 0.0500 | RX=0; 0.69 (0.57 to 0.85) RX=1; 1.17 (0.72 to 1.89) |
(52, 53)G |
| hsa-miR-550 | <0.0001 | 4.18 (2.31 to 7.56) | (54)O |
| hsa-miR-625 | 0.0119 | 2.48 (1.22 to 5.02) | (55)O |
| kshv-miR-k12-1 | 0.0023 | 2.08 (1.30 to 3.32) | (27)O |
| hsa-miR-10b | <0.0001 | 0.74 (0.64 to 0.85) | (6, 42, 43)G |
| hsa-miR-140 | 0.0130 | 1.57 (1.10 to 2.24) | (38, 39)G |
| hsa-miR-149 | 0.0056 | 0.76 (0.63 to 0.92) | (56)G |
C.I., Confidence Interval; RX=1 denotes radiation therapy alone, RX=0 denotes non-radiation therapy;
G
glioblastoma multiforme study;
O
study on any other type of cancer.