Table 3.
Fractures Observed (Obs)a Among 742 Olmsted County, MN Men Following Prostate Cancer First Diagnosed in 1990–99 Compared With the Numbers Expected (Exp) and Standardized Incidence Ratios (SIR), With 95% Confidence Intervals (CI)
| Fracture site | All fractures | Non-pathological, non-incidental fractures due to moderate trauma | ||||
|---|---|---|---|---|---|---|
| Obs | Exp | SIR (95% CI)b | Obs | Exp | SIR (95% CI) b | |
| Skull/face | 11 | 9.0 | 1.2 (0.6–2.2) | 7 | 4.3 | 1.6 (0.6–3.3) |
| Hands/fingers | 17 | 16.6 | 1.0 (0.6–1.6) | 5 | 7.4 | 0.7 (0.2–1.6) |
| Distal forearm | 21 | 7.6 | 2.8 (1.7–4.2) | 14 | 4.9 | 2.9 (1.6–4.8) |
| Other arm | 11 | 17.3 | 0.6 (0.3–1.1) | 5 | 11.9 | 0.4 (0.1–0.98) |
| Clavicle/scapula/sternum | 10 | 9.4 | 1.1 (0.5–1.9) | 4 | 5.2 | 0.8 (0.2–2.0) |
| Ribs | 67 | 38.5 | 1.7 (1.4–2.2) | 41 | 25.4 | 1.6 (1.2–2.2) |
| Thoracic/lumbar vertebrae | 145 | 18.2 | 8.0 (6.7–9.4) | 57 | 15.0 | 3.8 (2.9–4.9) |
| Cervical vertebrae | 10 | 3.5 | 2.9 (1.4–5.3) | 4 | 1.6 | 2.5 (0.7–6.5) |
| Pelvis | 15 | 8.0 | 1.9 (1.04–3.1) | 7 | 5.7 | 1.2 (0.5–2.5) |
| Proximal femur | 35 | 28.0 | 1.2 (0.9–1.7) | 27 | 24.3 | 1.1 (0.7–1.6) |
| Other leg | 28 | 22.2 | 1.3 (0.8–1.8) | 15 | 13.7 | 1.1 (0.6–1.8) |
| Feet/toes | 14 | 12.7 | 1.1 (0.6–1.8) | 5 | 2.7 | 1.8 (0.6–4.3) |
| Any site | 258 | 138 | 1.9 (1.6–2.1) | 139 | 102 | 1.4 (1.1–1.6) |
a
Note that the number of fractures observed at specific skeletal sites may differ from those reported in Table 2 because only the first fracture of each type per patient was counted in this analysis.
b
Statistically significant (p<.05) associations are bolded.