Table 1.
Characteristics of the study group.
| CTRL (n = 20) | SAP (n = 28) | AMI (n = 50) | P | |
|---|---|---|---|---|
| Age (years) (mean ± SD) | 44,6 ± 6,2 | 56,7 ± 11,6 | 58 ± 11,5 | P < 0.05 versus CTRL |
| Age (years) (median ± IQR) | 44 (34–54) | 56 (32–75) | 57 (30–79) | P < 0.05 versus CTRL |
| Male, n (%) | 17 (57) | 18 (60) | 30 (60) | P = NS |
| Hypertension, n (%) | 7 (23) | 17 (57) | 30 (60) | P < 0.05 versus CTRL |
| Hypercholesterolaemia, n (%) | 8 (26) | 23 (77) | 35 (70) | P < 0.05 versus CTRL |
| Type 2 diabetes mellitus, n (%) | 0 | 11 (36) | 18 (36) | P < 0.05 versus CTRL |
| Smoking, n (%) | 12 (40) | 19 (63) | 32 (64) | P < 0.05 versus CTRL |
| Family history of IHD, n (%) | 8 (27) | 13 (43) | 24 (48) | P < 0.05 versus CTRL |
| Statins prior to hospitalization, n (%) | 0 | 20 (67) | 32 (64) | P < 0.05 versus CTRL |
| ACE inhibitors, n (%) | 4 (13) | 16 (53) | 23 (46) | P < 0.05 versus CTRL |
| Acetylsalicylic acid, n (%) | 2 (7) | 28 (100) | 31 (62) | P < 0.05 versus CTRL, SAP |
| Total cholesterol [mg/dL] | 199 (156–256) | 201 (156–256) | 201,5 (122–313) | P = NS |
| HDL cholesterol [mg/dL] | 43 (20–70) | 43 (24–75) | 41 (13–74) | P = NS |
| LDL Cholesterol [mg/dL] | 97 (89–124) | 100 (65–216) | 105 (65–113) | P = NS |
| Triglycerides [mg/dL] | 150 (123–200) | 176,5 (84–269) | 163 (76–375) | P = NS |
| Creatinine [mg/dL] | 0,9 (0,7–1,4) | 0,9 (0,8–1,3) | 0,9 (0,7–14) | P = NS |
| Erythrocytes [×106/μL] | 4,7 (4,2–5,1) | 4,7 (4,3–5,1) | 4,62 (4,12–5,2) | P = NS |
| Leucocytes [×103/μL] | 6,9 (5,5–8,3) | 6,6 (5,2–7,4) | 10,17 ± 2,8 | P < 0.001 versus CTRL, SAP |
| Monocytes [×103/μL] | 0,8 (0,4–1,2) | 0,7 (0,46–1,14) | 0,76 (0,41–1,1) | P = NS |
| Platelets [×103/μL] | 195 (143–246) | 194 (137–251) | 198 (146–250) | P = NS |
|
| ||||
| Initial LVEF ≤40%, n (%) | — | — | 14 (28) | |
| Initial CKMB [U/l] | — | — | 26,5 (5–136) | |
| Initial TnI [ng/mL] | — | — | 0,7 (0,0–18) | |
| Maximal CKMB [U/l] | — | — | 109,5 (5–572) | |
| Maximal TnI [ng/mL] | — | — | 4,7 (0,92–72) | |
| Anterior wall infarction, n (%) | — | — | 30 (60) | |
| Multivessel CAD, n (%) | — | — | 26 (52) | |