Table 1. Demographic data, clinical features of infection, and laboratory values in 14 cases of Plasmodium falciparum malaria and 16 cases of PCR-confirmed P. knowlesi malaria in children, Kudat, Malaysia, January 1–November 30, 2009*.
| Characteristic | P. knowlesi, n =16 | P. falciparum, n =14 | p value |
|---|---|---|---|
| Age, y | |||
| Mean (SD) | 8.9 (2.5) | 5.4 (3.2) | 0.002 |
| Range |
4–14 |
0.75–11 |
|
| Male sex, no. (%) |
8 (50) |
7 (50) |
1.00 |
| Living in Banggi, no. (%) |
0 (0) |
10 (71.4) |
<0.001
|
| Duration of fever, d, median (IQR) |
4 (3–6) |
6.5 (4–7) |
0.12 |
| Examination findings at admission | |||
| Temperature, oC, median (IQR) | 37.9 (37.0–39.1) | 37.0 (37.0–37.4) | 0.07 |
| Heart rate, beats/min, mean (SD) | 110 (24) | 119 (15) | 0.24 |
| Respiratory rate, beats/min, mean (SD) | 27.8 (3.9) | 32 (3.8) | 0.01 |
| Systolic blood pressure, mm Hg, mean (SD) |
105 (8.3) |
98 (11.2) |
0.06 |
| Laboratory results | |||
| Hemoglobin d 0, g/dL, median (IQR) | 10.7 (10.0–11.4) | 8.5 (6.1–10.5) | 0.001 |
| Hemoglobin minimum level, g/dL, median (IQR) | 9.7 (8.4–10.2) | 7.15 (6.1–9.3) | 0.035 |
| Day of hemoglobin minimum level, mean (SD) | 2.6 (1.03) | 1.5 (1.3) | 0.022 |
| Lymphocyte count d 0, × 103/µL, median (IQR) | 2.0 (1.7–2.3) | 2.5 (2.0–4.6) | 0.09 |
| Lymphocyte minimum level, × 103/µL, median (IQR) | 1.6 (1.3–2.2) | 2.4 (1.9–3.9) | 0.01 |
| Day of lymphocyte minimum level, median (IQR) | 1 (0–1) | 1.5 (0–3) | 0.19 |
| Thrombocyte count d 0, × 103/µL, median (IQR) | 89.5 (72.0–118.5) | 171.5 (98–271) | 0.038 |
| Thrombocyte count minimum level, × 103/µL, median (IQR) | 76.5 (68.5–110.0) | 156 (98–227) | 0.014 |
| Day of thrombocyte count minimum level, median (IQR) | 1 (1–1) | 0.5 (0–2) | 0.67 |
*IQR, interquartile range. Boldface indicates statistical significance.