Table 2. Malaria treatment according to Plasmodium species and response to treatment in children, Kudat, Malaysia, January 1–November 30, 2009*.
| Species and treatment regimen | No. (%) patients | Days until negative smear† |
|---|---|---|
| P. knowlesi, n = 16 | ||
| 3 days CQ/PQ | 13 (81) | 2 (2–3, 1–5) |
| Oral Q | 2 (13) | 2, 2 |
| IV Q | 1 (6) | 2 |
| All |
|
2 (2–3, 1–5) |
| P. falciparum, n = 14 | ||
| 3 days CQ/PQ → oral Q | 2 (14) | 5, 5 |
| Oral Q → AL | 1 (7) | 3 |
| SP/PQ → AM | 1 (7) | 8 |
| SP/PQ | 2 (14) | 1, 2 |
| SP/PQ → CQ/Q → AL | 1 (7) | 3 |
| SP/PQ → CQ/IV Q → AL | 1 (7) | 5 |
| SP/PQ → CQ/IV Q → oral Q | 1 (7) | 3 |
| SP/PQ → oral Q → IV Q → oral Q | 1 (7) | 16 |
| IV Q → oral Q | 2 (14) | 1, 10 |
| IV Q → oral Q/PQ | 1 (7) | 11 |
| Oral Q/PQ → AM | 1 (7) | 10 |
| All | 5 (3–10, 1–16)‡ |
*IQR, interquartile range; CQ, chloroquine; PQ, primaquine; Q, quinine; IV, intravenous; AL, artemether/lumefantrine; SP, sulfamethoxazole/pyrimethamine; AM, artesunate/mefloquine. †Values are mean (IQR, range) by category or days by patient. ‡p value = 0.009 for days until negative smear for P. falciparum vs. P. knowlesi.