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Changes in renal morphology in WT and TRPV1−/− mice after 4 wks of deoxycorticosterone acetate (DOCA)-salt treatment. Representative PAS-stained (A) or Masson trichrome–stained (B) kidney sections showing glomerulosclerosis or tubulointerstitial injury in control WT and TRPV1−/− mice (a and b), and WT and TRPV1−/− mice (c and d) treated with DOCA-salt. Magnification, 400× (A) or 200× (B).
